In the Nutrition Genome Report, you may see a reference to the genes of MTHFR 1298 and BH4, VDR, thyroid hormones, MAO-A and serotonin/estrogen, COMT and estrogen, dopamine and adrenaline and the CYP liver enzymes. Below you can see how they are all related in shared pathways, and why it is important to look at all of the genes working as whole.

 

BH4 Cycle, COMT, MAO-A

Sources

1. M. Whirl-Carrillo, E.M. McDonagh, J. M. Hebert, L. Gong, K. Sangkuhl, C.F. Thorn, R.B. Altman and T.E. Klein. “Pharmacogenomics Knowledge for Personalized Medicine” Clinical Pharmacology & Therapeutics (2012) 92(4): 414-417.

2. Advanced Medical Biochemistry