What is the CBS Gene? The Cystathione Beta-Synthase (CBS) enzyme pulls homocysteine to hydrogen sulfide (H2S) and glutathione, requiring B6 and SAMe as a modulator. Interruptions in this process may be connected to digestive disorders, intolerance to sulfur rich...

What is MTRR? Methionine synthase reductase (MTRR) is a vital enzyme of the homocysteine/methionine metabolic pathway and is required for the conversion of the inactive form of methionine synthase (MTR) to its active form. MTRR helps recycle B12. The MTRR enzyme...

What is COMT? COMT (Catechol-O-Methyltransferase) breaks down estrogen, catecholamines and neurotransmitters including dopamine, epinephrine and norepinephrine. Heterozygous or homozygous variants for the COMT V158M methionine allele slow down the COMT enzyme,...

What is MAO-A? MAO-A (Monoamine oxidase A) is a critical enzyme involved in breaking down important neurotransmitters such as serotonin, norepinephrine, and dopamine. Males can only have a heterozygous MAO-A, while females can have heterozygous or homozygous variants....

What is the MTHFR A128C Gene? Unlike MTHFR C677T, MTHFR 1298 is not linked to elevated homocysteine levels unless there is a heterozygous MTHFR 1298 and MTHFR 677 together. Disruptions in both MTHFR genes may lead to lower levels of tetrahydrobiopterin BH4.  The...

The Story of the Cell Membrane and Mitochondria "Cancer arises from a single abnormal cell." Dr. Joe Lipsick, Professor of Pathology and Genetics at Stanford University  Imagine your cell is like your own personal kingdom. The nucleus and the mitochondria are the King...