What is MTHFR C677T? Methylenetetrahydrofolate Reductase is labeled for both an enzyme and a gene. The MTHFR C677T gene produces a functioning MTHFR enzyme that converts methyfolate to 5-MTHF and helps regulate homocysteine levels. If the MTHFR C677T gene has...

The International Journal of Medicine published a commentary in late April 2020 titled, “Does apolipoprotein E genotype predict COVID-19 severity?” The researchers argue that it is possible that having one or two copies of APOE-E4 allele predisposes one to be at high...

In the 1930s, people's lifetime risk in the U.S. of developing invasive malignant melanoma was 1 in 1,500. Currently, the risk is 1 in 59. From 2012 to 2022, the number of new invasive melanoma cases diagnosed annually increased by 31 percent. For non-melanoma skin...

APOE and Progesterone In the Nutrition Genome Report, there is a slider in the Hormone section for women called Progesterone and Fertility. APOE is a significant cholesterol precursor supplier to produce ovarian estrogen and progesterone. Women with at least one...

World Infertility Awareness Month is observed every June to increase awareness of infertility worldwide. This week we will look at two genes that are strongly correlated with environmental pressure: HFE and Tp53. The HFE Gene and Fertility  The human hemochromatosis...

World Infertility Awareness Month is celebrated every June to increase awareness of infertility worldwide. For week 2 of the series, we will be reviewing the research on folate metabolism, choline metabolism, and infertility. Review the MTHFR and PEMT Genes Variants...