What is MTHFR C677T? Methylenetetrahydrofolate Reductase is labeled for both an enzyme and a gene. The MTHFR C677T gene produces a functioning MTHFR enzyme that converts methyfolate to 5-MTHF and helps regulate homocysteine levels. If the MTHFR C677T gene has...
The International Journal of Medicine published a commentary in late April 2020 titled, “Does apolipoprotein E genotype predict COVID-19 severity?” The researchers argue that it is possible that having one or two copies of APOE-E4 allele predisposes one to be at high...
In the 1930s, people’s lifetime risk in the U.S. of developing invasive malignant melanoma was 1 in 1,500. Currently, the risk is 1 in 59. From 2012 to 2022, the number of new invasive melanoma cases diagnosed annually increased by 31 percent. For non-melanoma...
APOE and Progesterone In the Nutrition Genome Report, there is a slider in the Hormone section for women called Progesterone and Fertility. APOE is a significant cholesterol precursor supplier to produce ovarian estrogen and progesterone. Women with at least one...
World Infertility Awareness Month is observed every June to increase awareness of infertility worldwide. This week we will look at two genes that are strongly correlated with environmental pressure: HFE and Tp53. The HFE Gene and Fertility The human hemochromatosis...
World Infertility Awareness Month is celebrated every June to increase awareness of infertility worldwide. For week 2 of the series, we will be reviewing the research on folate metabolism, choline metabolism, and infertility. Review the MTHFR and PEMT Genes Variants...
Analyzing the Nutrition Genome Report for Infertility: World Infertility Awareness Month is celebrated every June to increase awareness of infertility worldwide. From 1960 to 2019, global fertility rates dropped more than 10 percent per decade and more than 50 percent...
Anxiety disorders affect approximately 18% of adults. Anxiety and fear are connected to numerous genetic and epigenetic factors that have been shaped over generations and life experiences. Trauma makes deep imprints on the genome to recognize threats to your...
Mental Health Awareness Month is observed in May to increase the awareness of those struggling with mental health. Each week this month, we will be exploring how to use the Nutrition Genome Report to help your patients with their mental health. Lactose and Genetics...
In November 2021, we added HLA2.5 and HLA-DQ8 to the Nutrition Genome Report. Published research shows that approximately 30-40 percent of the general population have variants in the celiac disease risk HLA genes, yet only 3% of these individuals develop celiac...
COMT V158M is most known for understanding the variation of dopamine’s baseline level and metabolic breakdown. Heterozygous or homozygous variants for the COMT V158M gene slow down the COMT enzyme, affecting estrogen metabolism and the breakdown of dopamine and...
Do you take fish oil? Did you know that your APOE genotype may determine the response to DHA supplementation? Dr. Rhonda Patrick published a study with a hypothesis on why APOE-e4 carriers respond well to the DHA present in fish and fish roe but do not respond as well...
