One of the most common questions we get is “what is the difference between the Nutrition Genome DNA Collection Kit and Genetic Report and the 23andme version of the Nutrition Genome Report?” First, we want to point out that we only recommend running the V4 23andme files from before August 2017.
In August 2017, 23andme made a change to their DNA file that removed numerous genes that are important for nutrigenomic testing. Since 23andme is mainly an ancestry company with a focus on selling DNA data, this didn’t affect their testing. However, for companies that test genetic SNPs related to the field of nutrigenomics, it removed quite a few genes.
Nutrition Genome launched a proprietary cheek-swab DNA test kit in November 2017 that could easily accommodate toddlers through seniors. We made this decision so that we could be in control of the genes we test, and we could provide a testing alternative that also did not sell the data to a third party.
Along with our new launch, we also created a completely new format for the Nutrition Genome Report and upgraded the report with new research and more proactive recommendations. We exist to empower you in your journey to optimal health, and we are confident that our new test kit and report bundle is the most comprehensive genetic analysis on the market.
Previews of Both Nutrition Genome Reports
Here is a preview of the 23andme Nutrition Genome Sample Report 2017.
Here is a preview of the Nutrition Genome Report 2022 from the DNA Collection Kit and Genetic Report version.
The new version will continue to get updates for new genes and research, while the 23andme version will no longer be updated.
Nutrition Genome’s DNA Kit and Genetic Analysis, V4 23andme Report, and V5 23andme Report SNP Differences
| Nutrition Genome DNA Collection Kit and Genetic Report | V4 23andme Nutrition Genome Report (Before August 2017) | V5 23andme Nutrition Genome Report (After August 2017) |
| Currently tests 100 Genes and 113 SNPs | Missing 22 genes. See Below. | Missing 38 genes. See Below. |
| Continually updated with new genes and research | No longer updated as of November 2017 | No longer updated as of November 2017 |
Genes Tested for Each Nutrition Genome Report
Here is a list of all the genes tested in the Nutrition Genome Report for the DNA Collection Kit and Genetic Report, the V4 23andme file, and V5 23andme file.
| Nutrition Genome DNA Collection Kit and Genetic Report | V4 23andme Nutrition Genome Report (Before August 2017) | V5 23andme Nutrition Genome Report (After August 2017) |
| 5-HT2A | *Missing | *Missing |
| 9p21 | 9p21 | 9p21 |
| ABCG2 (Q141K) | ABCG2 (Q141K) | ABCG2 (Q141K) |
| ACE1 | *Missing | *Missing |
| ACE2 | *Missing | *Missing |
| ACAT1-02 | ACAT1-02 | *Missing |
| ACSL1 | *Not available | *Not available |
| ACTN3 R577X | *Not available | *Not available |
| ADD1 | ADD1 | ADD1 |
| ADIPOQ | ADIPOQ | *Missing |
| ADRB2 | ADRB2 | ADRB2 |
| AGTR1 | *Missing | *Missing |
| ALDH2 | *Missing | *Missing |
| ANKK1 | ANKK1 | ANKK1 |
| APB1 (DAO) | APB1 (DAO) | APB1 (DAO) |
| APOA2 | APOA2 | APOA2 |
| APOE | APOE | APOE |
| ARMS2 | ARMS2 | ARMS2 |
| ATM D1853N | ATM D1853N | ATM D1853N |
| BCMO1 A379V | BCMO1 A379V | BCMO1 A379V |
| BCMO1 R267S | BCMO1 R267S | BCMO1 R267S |
| BDNF | BDNF | BDNF |
| CAT C-262T | *Missing | *Missing |
| CBS | CBS | CBS |
| CFH | CFH | CFH |
| COL1A1 | COL1A1 | COL1A1 |
| COMT V158M | COMT V158M | COMT V158M |
| COQ2 | COQ2 | COQ2 |
| CTH | CTH | *Missing |
| CYP1A1*2C A4889G | CYP1A1*2C A4889G | CYP1A1*2C A4889G |
| CYP1A2 C164A | CYP1A2 C164A | CYP1A2 C164A |
| CYP1B1*6 L432V | CYP1B1*6 L432V | CYP1B1*6 L432V |
| CYP2C19*17 | CYP2C19*17 | CYP2C19*17 |
| CYP2C9*2 C430T | CYP2C9*2 C430T | *Missing |
| CYP2C9*3 A1075C | CYP2C9*3 A1075C | CYP2C9*3 A1075C |
| CYP2D6 T100C | CYP2D6 T100C | *Missing |
| CYP2E1 | CYP2E1 | CYP2E1 |
| CYP2R1 | CYP2R1 | CYP2R1 |
| CYP3A4*1B | CYP3A4*1B | CYP3A4*1B |
| DHFR A20965G | DHFR A20965G | *Missing |
| DHFR C19483A | DHFR C19483A | *Missing |
| DI01 | DI01 | DI01 |
| DI02 | DI02 | *Missing |
| ESR2 | ESR2 | ESR2 |
| F5 | F5 | F5 |
| FAAH | *Missing | *Missing |
| FADS1 | FADS1 | FADS1 |
| FADS2 | FADS2 | FADS2 |
| FTO | *Not available | *Not available |
| FUT2 | FUT2 | FUT2 |
| GAD1 | GAD1 | *Majority are missing and affects GAD1 analysis |
| GATA3 | *Missing | *Missing |
| GPX1 | *Not available | *Not available |
| GSTM1 rs366631 | *Not available | *Not available |
| GSTP1 A114V | GSTP1 A114V | GSTP1 A114V |
| GSTP1 I105V | GSTP1 I105V | GSTP1 I105V |
| HFE-C282Y | HFE-C282Y | HFE-C282Y |
| HFE-H63D | HFE-H63D | HFE-H63D |
| HLA DQ2.5 | *Not available | *Not available |
| HLA DQ8 | *Not available | *Not available |
| HMNT | HMNT | HMNT |
| IL6 | *Not available | *Not available |
| LCT | LCT | LCT |
| LPA | LPA | LPA |
| LZTFL1 | *Missing | *Missing |
| MAO-A | MAO-A | MAO-A |
| *Not available | MAT1 | MAT1 |
| MDM2 | MDM2 | *Missing |
| MLH1 | MLH1 | MLH1 |
| MTHFD1 G1958A | MTHFD1 G1958A | MTHFD1 G1958A |
| MTHFR A1298C | MTHFR A1298C | MTHFR A1298C |
| MTHFR C677T | MTHFR C677T | MTHFR C677T |
| MTNR1B | *Not available | *Not available |
| MTR A2756G | MTR A2756G | MTR A2756G |
| MTRR A66G | MTRR A66G | MTRR A66G |
| NBPF3 | NBPF3 | NBPF3 |
| NAT2 | *Missing | *Missing |
| NOS1 | NOS1 | NOS1 |
| NOS2 | NOS2 | NOS2 |
| PEMT | PEMT | PEMT |
| PON1 | PON1 | PON1 |
| PPAR-alpha | *Not available | *Not available |
| PPARGC1A | PPARGC1A | PPARGC1A |
| PPCDC | *Not available | *Not available |
| SELENBP1 | *Not available | *Not available |
| SHBG | SHBG | SHBG |
| SIRT1 | *Missing | *Missing |
| SLC17A7 | *Missing | *Missing |
| SLC23A1 | SLC23A1 | SLC23A1 |
| SOD2 | SOD2 | SOD2 |
| SOD3 | SOD3 | *Missing |
| TCF7L2 | TCF7L2 | TCF7L2 |
| TCN2 C766G | TCN2 C766G | *Missing |
| TFR2 | *Missing | *Missing |
| TMPRSS2 | *Missing | *Missing |
| TNFA | TNFA | TNFA |
| TP53 | TP53 | TP53 |
| VKORC1*2 | VKORC1*2 | VKORC1*2 |
| XRCC3 | *Not available | *Not available |
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