The methylation cycle diagram gives you a visual on how all of the genes related to folate, B6, B12, B2, choline and betaine are working together for optimal gene expression. This diagram is to serve as a study tool for an in-depth understanding of discovering where in the methylation cycle that you need the most assistance based on your Nutrition Genome Report. Here is where you can see the increased vitamin needs for SNP’s that may cause reduced enzymatic function and lead to low levels of folate, choline and elevated homocysteine.